Alzheimer's disease (AD) is the most common age-related dementia. Unfortunately due to a
lack of validated biomarkers definitive diagnosis relies on the histological demonstration of …

Background Soluble amyloid-β (Aβ) oligomers are the major toxic substances associated
with the pathology of Alzheimer's disease (AD). The ability to measure Aβ oligomer levels in …

Amyloid-β (Aβ) deposits are important pathological hallmarks of Alzheimer's disease (AD).
Aβ aggregates into fibrils; however, the intermediate oligomers are believed to be the most …

Recent studies indicate that small amyloid-β peptide (Aβ) oligomers are the major toxic
species responsible for development and progression of Alzheimer's disease (AD) …

Amyloid-β (Aβ) oligomers are heterogeneous and instable compounds of variable molecular
weight. Flow cytometry and fluorescence resonance energy transfer (FRET)-based methods …

Since its discovery, amyloid‐β (Aβ) has been the principal target of investigation of in
Alzheimer's disease (AD). Over the years however, no clear correlation was found between …

Diagnostic measures for Alzheimer's disease (AD) commonly rely on evaluating the levels of
amyloid-(A) peptides within the cerebrospinal fluid (CSF) of affected individuals. These …

There is accumulating evidence that soluble amyloid‐β (Aβ) oligomers, rather than amyloid
fibrils, are the principal pathogenic species in Alzheimer disease (AD). Here, we have …

Alzheimer's disease (AD) is the most common neurodegenerative disorder, characterized by
neuronal impairment leading to dramatic changes in brain. Amyloid-β peptides and tau …

The causative role of amyloid β 1–42 (Aβ42) aggregation in the pathogenesis of Alzheimer's
disease (AD) has been under debate for over 25 years. Primarily, scientific efforts have …