The neuroscience of placebo effects: connecting context, learning and health
Placebo effects are beneficial effects that are attributable to the brain–mind responses to the
context in which a treatment is delivered rather than to the specific actions of the drug. They …
context in which a treatment is delivered rather than to the specific actions of the drug. They …
Placebo and the new physiology of the doctor-patient relationship
F Benedetti - Physiological reviews, 2013 - journals.physiology.org
Modern medicine has progressed in parallel with the advancement of biochemistry,
anatomy, and physiology. By using the tools of modern medicine, the physician today can …
anatomy, and physiology. By using the tools of modern medicine, the physician today can …
[HTML][HTML] An fMRI-based neurologic signature of physical pain
Background Persistent pain is measured by means of self-report, the sole reliance on which
hampers diagnosis and treatment. Functional magnetic resonance imaging (fMRI) holds …
hampers diagnosis and treatment. Functional magnetic resonance imaging (fMRI) holds …
[HTML][HTML] Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data
The brain systems underlying placebo analgesia are insufficiently understood. Here we
performed a systematic, participant-level meta-analysis of experimental functional …
performed a systematic, participant-level meta-analysis of experimental functional …
Mindfulness meditation-based pain relief employs different neural mechanisms than placebo and sham mindfulness meditation-induced analgesia
Mindfulness meditation reduces pain in experimental and clinical settings. However, it
remains unknown whether mindfulness meditation engages pain-relieving mechanisms …
remains unknown whether mindfulness meditation engages pain-relieving mechanisms …
[HTML][HTML] Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations
There is tremendous interpatient variability in the response to analgesic therapy (even for
efficacious treatments), which can be the source of great frustration in clinical practice. This …
efficacious treatments), which can be the source of great frustration in clinical practice. This …
[PDF][PDF] Placebo analgesia: a predictive coding perspective
This Perspective reviews recent findings in placebo hypoalgesia and provides a conceptual
account of how expectations and experience can lead to placebo hypoalgesia. In particular …
account of how expectations and experience can lead to placebo hypoalgesia. In particular …
Neuro-bio-behavioral mechanisms of placebo and nocebo responses: implications for clinical trials and clinical practice
The placebo effect has often been considered a nuisance in basic and particularly clinical
research. This view has gradually changed in recent years due to deeper insight into the …
research. This view has gradually changed in recent years due to deeper insight into the …
The placebo effect: from concepts to genes
B Colagiuri, LA Schenk, MD Kessler, SG Dorsey… - Neuroscience, 2015 - Elsevier
Despite its initial treatment as a nuisance variable, the placebo effect is now recognized as a
powerful determinant of health across many different diseases and encounters. This is in …
powerful determinant of health across many different diseases and encounters. This is in …
[PDF][PDF] Placebo effects: from the neurobiological paradigm to translational implications
F Benedetti - Neuron, 2014 - cell.com
Today we are witnessing a new science of placebo, a complex discipline that encompasses
several experimental approaches and translational implications. Modern neurobiological …
several experimental approaches and translational implications. Modern neurobiological …