Brain injury in premature infants is of enormous public health importance because of the
large number of such infants who survive with serious neurodevelopmental disability …

BACKGROUND During early mammalian brain development, transient neurons and circuits
form the scaffold for the development of neuronal networks. In the immature cerebral cortex …

More than 95 percent of infants who have neonatal stroke survive to adulthood, and many
have residual motor or cognitive disabilities. This article makes the point that recognition of …

Prematurity, especially preterm birth (less than 32 weeks' gestation), is common and
associated with high rates of both survival and neurodevelopmental disability, especially …

Background Congenital heart disease in newborns is associated with global impairment in
development. We characterized brain metabolism and microstructure, as measures of brain …

Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

Epileptogenesis is defined as the process of developing epilepsy—a disorder characterized
by recurrent seizures—following an initial insult. Seizure incidence during the human …

The field of neonatal neurology, and specifically its focus on the premature infant, had its
inception in neuropathologic studies. Since then, the development of advanced imaging …

The majority of infants born very preterm (24–32 wk gestational age) now survive; however,
long-term neurodevelopmental and behavioral problems remain a concern. As part of their …

Historically the major focus in neonatal neurology has been on brain injury in premature
infants born less than 30 gestational weeks. This focus reflects the urgent need to improve …