[PDF][PDF] Spontaneous activity in developing thalamic and cortical sensory networks
Developing sensory circuits exhibit different patterns of spontaneous activity, patterns that
are related to the construction and refinement of functional networks. During the …
are related to the construction and refinement of functional networks. During the …
Mechanisms underlying development of visual maps and receptive fields
AD Huberman, MB Feller, B Chapman - Annu. Rev. Neurosci., 2008 - annualreviews.org
Patterns of synaptic connections in the visual system are remarkably precise. These
connections dictate the receptive field properties of individual visual neurons and ultimately …
connections dictate the receptive field properties of individual visual neurons and ultimately …
Differential progression of structural and functional alterations in distinct retinal ganglion cell types in a mouse model of glaucoma
L Della Santina, DM Inman, CB Lupien… - Journal of …, 2013 - Soc Neuroscience
Intraocular pressure (IOP) elevation is a principal risk factor for glaucoma. Using a
microbead injection technique to chronically raise IOP for 15 or 30 d in mice, we identified …
microbead injection technique to chronically raise IOP for 15 or 30 d in mice, we identified …
[HTML][HTML] Retinotopic map refinement requires spontaneous retinal waves during a brief critical period of development
During retinocollicular map development, spontaneous waves of action potentials spread
across the retina, correlating activity among neighboring retinal ganglion cells (RGCs). To …
across the retina, correlating activity among neighboring retinal ganglion cells (RGCs). To …
Connecting the retina to the brain
The visual system is beautifully crafted to transmit information of the external world to visual
processing and cognitive centers in the brain. For visual information to be relayed to the …
processing and cognitive centers in the brain. For visual information to be relayed to the …
[PDF][PDF] A conserved switch in sensory processing prepares developing neocortex for vision
MT Colonnese, A Kaminska, M Minlebaev, M Milh… - Neuron, 2010 - cell.com
Developing cortex generates endogenous activity that modulates the formation of functional
units, but how this activity is altered to support mature function is poorly understood. Using …
units, but how this activity is altered to support mature function is poorly understood. Using …
Sparsification of neuronal activity in the visual cortex at eye-opening
NL Rochefort, O Garaschuk, RI Milos… - Proceedings of the …, 2009 - National Acad Sciences
Eye-opening represents a turning point in the function of the visual cortex. Before eye-
opening, the visual cortex is largely devoid of sensory inputs and neuronal activities are …
opening, the visual cortex is largely devoid of sensory inputs and neuronal activities are …
Selective vulnerability of specific retinal ganglion cell types and synapses after transient ocular hypertension
Key issues concerning ganglion cell type-specific loss and synaptic changes in animal
models of experimental glaucoma remain highly debated. Importantly, changes in the …
models of experimental glaucoma remain highly debated. Importantly, changes in the …
Role of emergent neural activity in visual map development
Highlights•Retinal waves drive visual circuits before the onset of visual experience.•Map
development in the midbrain, thalamus and cortex is regulated by retinal …
development in the midbrain, thalamus and cortex is regulated by retinal …
[PDF][PDF] Distinct roles for spontaneous and visual activity in remodeling of the retinogeniculate synapse
Sensory experience and spontaneous activity play important roles in development of
sensory circuits; however, their relative contributions are unclear. Here, we test the role of …
sensory circuits; however, their relative contributions are unclear. Here, we test the role of …