GABAA Receptor Channels

RL Macdonald, RW Olsen - Annual review of neuroscience, 1994 - annualreviews.org
… Endo S, Olsen RW. Preparation of antibodies to beta subunits of GABA A recep tors.
Neurochem. 59: 1444-51 Endo S, Olsen RW. Antibodies specific for a subunit subtypes of GABAA …

International Union of Pharmacology. XV. Subtypes of γ-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function

EA Barnard, P Skolnick, RW Olsen, H Mohler… - Pharmacological …, 1998 - ASPET
This article does not aim to review in detail the properties of-aminobutyric acidA (GABAA) b
receptors, because recent accounts of that topic are available. In this same journal, a review …

Molecular biology of GABAA receptors

RW Olsen, AJ Tobin - The FASEB Journal, 1990 - Wiley Online Library
The major type of receptor for the inhibitory neurotransmitter γ‐aminobutyric acid (GABA),
called the GABA A receptor, is a member of a gene superfamily of ligand‐gated ion channels. …

GABAA receptors: subtypes provide diversity of function and pharmacology

RW Olsen, W Sieghart - Neuropharmacology, 2009 - Elsevier
… This list was first presented by Olsen & Sieghart (in press). … subtype as a native receptor,
and our current opinion of which subtypes meet these criteria (Olsen and Sieghart, in press). …

International Union of Pharmacology. LXX. Subtypes of γ-aminobutyric acidA receptors: classification on the basis of subunit composition, pharmacology, and function …

RW Olsen, W Sieghart - Pharmacological reviews, 2008 - ASPET
In this review we attempt to summarize experimental evidence on the existence of defined
native GABA A receptor subtypes and to produce a list of receptors that actually seem to exist …

A nomenclature for ligand-gated ion channels

GL Collingridge, RW Olsen, J Peters, M Spedding - Neuropharmacology, 2009 - Elsevier
The ligand-gated ion channels that participate in fast synaptic transmission comprise the
nicotinic acetylcholine, 5-hydroxytryptamine 3 (5-HT 3 ), γ-aminobutyric acid A (GABA A ), …

GABAA-receptor-associated protein links GABAA receptors and the cytoskeleton

H Wang, FK Bedford, NJ Brandon, SJ Moss, RW Olsen - Nature, 1999 - nature.com
Type-A receptors for the neurotransmitter GABA (γ-aminobutyric acid) are ligand-gated
chloride channels that mediate inhibitory neurotransmission. Each subunit of the pentameric …

Functional domains of GABAA receptors

GB Smith, RW Olsen - Trends in pharmacological sciences, 1995 - cell.com
… In this article, Geoffrey Smith and Richard Olsen discuss recent affinity labelling and
sitedirected mutagenesis studies on GABA A receptors that have identified amino acid residues …

Mice lacking the β3 subunit of the GABAA receptor have the epilepsy phenotype and many of the behavioral characteristics of Angelman syndrome

…, GD Ellison, RW Olsen - Journal of …, 1998 - Soc Neuroscience
Angelman syndrome (AS) is a severe neurodevelopmental disorder resulting from a deletion/mutation
in maternal chromosome 15q11–13. The genes in 15q11–13 contributing to the …

Mice devoid of γ-aminobutyrate type A receptor β3 subunit have epilepsy, cleft palate, and hypersensitive behavior

…, C Ferguson, K Snyder, RW Olsen - Proceedings of the …, 1997 - National Acad Sciences
γ-Aminobutyric acid type A receptors (GABA A -Rs) mediate the bulk of rapid inhibitory synaptic
transmission in the central nervous system. The β3 subunit is an essential component of …