User profiles for M. T. Cencioni

Maria Teresa Cencioni

Imperial College London
Verified email at imperial.ac.uk
Cited by 1892

B cells in multiple sclerosis—from targeted depletion to immune reconstitution therapies

MT Cencioni, M Mattoscio, R Magliozzi… - Nature Reviews …, 2021 - nature.com
Increasing evidence indicates the involvement of B cells in the pathogenesis of multiple
sclerosis (MS), but their precise roles are unclear. In this Review, we provide an overview of the …

[HTML][HTML] Immune reconstitution following autologous hematopoietic stem cell transplantation for multiple sclerosis: a review on behalf of the EBMT autoimmune …

MT Cencioni, A Genchi, G Brittain, TI de Silva… - Frontiers in …, 2022 - frontiersin.org
Multiple sclerosis (MS) is a central nervous system (CNS) disorder, which is mediated by an
abnormal immune response coordinated by T and B cells resulting in areas of inflammation, …

Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis

…, A Bergamaschi, MT Cencioni… - Journal of …, 2009 - Soc Neuroscience
Neurodegeneration is the irremediable pathological event occurring during chronic
inflammatory diseases of the CNS. Here we show that, in experimental autoimmune …

[HTML][HTML] Anandamide Suppresses Proliferation and Cytokine Release from Primary Human T-Lymphocytes Mainly via CB2 Receptors

MT Cencioni, V Chiurchiù, G Catanzaro, G Borsellino… - PloS one, 2010 - journals.plos.org
Background Anandamide (AEA) is an endogenous lipid mediator that exerts several effects
in the brain as well as in peripheral tissues. These effects are mediated mainly by two types …

Reversible CD8 T cell–neuron cross-talk causes aging-dependent neuronal regenerative decline

L Zhou, G Kong, I Palmisano, MT Cencioni, M Danzi… - Science, 2022 - science.org
Aging is associated with increased prevalence of axonal injuries characterized by poor
regeneration and disability. However, the underlying mechanisms remain unclear. In our …

Safety, tolerability, and activity of mesenchymal stem cells versus placebo in multiple sclerosis (MESEMS): a phase 2, randomised, double-blind crossover trial

…, L Castellan, M Cellerino, MT Cencioni… - The Lancet …, 2021 - thelancet.com
Background Mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells,
have been proposed as a promising therapeutic option for people with multiple sclerosis on …

Distinct modulation of human myeloid and plasmacytoid dendritic cells by anandamide in multiple sclerosis

V Chiurchiu, MT Cencioni, E Bisicchia… - Annals of …, 2013 - Wiley Online Library
Objective The immunopathogenesis of multiple sclerosis (MS) has always been thought to
be driven by chronically activated and autoreactive Th‐1 and Th‐17 cells. Recently, dendritic …

Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models

…, A Gentile, S Capsoni, MT Ciotti, MT Cencioni… - Molecular and Cellular …, 2008 - Elsevier
Biochemical modifications of tau proteins have been proposed to be among the earliest
neurobiological changes in Alzheimer's disease (AD) and correlate better with cognitive …

[HTML][HTML] BRCA1, PARP1 and γH2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib

…, S Lavorgna, DF Angelini, MT Cencioni… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Olaparib (AZD-2281, Ku-0059436) is an orally bioavailable and well-tolerated poly(ADP-ribose)
polymerase (PARP) inhibitor currently under investigation in patients with solid tumors. …

[HTML][HTML] Acute focal brain damage alters mitochondrial dynamics and autophagy in axotomized neurons

V Cavallucci, E Bisicchia, MT Cencioni, A Ferri… - Cell death & …, 2014 - nature.com
Mitochondria are key organelles for the maintenance of life and death of the cell, and their
morphology is controlled by continual and balanced fission and fusion dynamics. A balance …