User profiles for M. T. Cencioni
Maria Teresa CencioniImperial College London Verified email at imperial.ac.uk Cited by 1892 |
B cells in multiple sclerosis—from targeted depletion to immune reconstitution therapies
MT Cencioni, M Mattoscio, R Magliozzi… - Nature Reviews …, 2021 - nature.com
Increasing evidence indicates the involvement of B cells in the pathogenesis of multiple
sclerosis (MS), but their precise roles are unclear. In this Review, we provide an overview of the …
sclerosis (MS), but their precise roles are unclear. In this Review, we provide an overview of the …
[HTML][HTML] Immune reconstitution following autologous hematopoietic stem cell transplantation for multiple sclerosis: a review on behalf of the EBMT autoimmune …
MT Cencioni, A Genchi, G Brittain, TI de Silva… - Frontiers in …, 2022 - frontiersin.org
Multiple sclerosis (MS) is a central nervous system (CNS) disorder, which is mediated by an
abnormal immune response coordinated by T and B cells resulting in areas of inflammation, …
abnormal immune response coordinated by T and B cells resulting in areas of inflammation, …
Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis
…, A Bergamaschi, MT Cencioni… - Journal of …, 2009 - Soc Neuroscience
Neurodegeneration is the irremediable pathological event occurring during chronic
inflammatory diseases of the CNS. Here we show that, in experimental autoimmune …
inflammatory diseases of the CNS. Here we show that, in experimental autoimmune …
[HTML][HTML] Anandamide Suppresses Proliferation and Cytokine Release from Primary Human T-Lymphocytes Mainly via CB2 Receptors
MT Cencioni, V Chiurchiù, G Catanzaro, G Borsellino… - PloS one, 2010 - journals.plos.org
Background Anandamide (AEA) is an endogenous lipid mediator that exerts several effects
in the brain as well as in peripheral tissues. These effects are mediated mainly by two types …
in the brain as well as in peripheral tissues. These effects are mediated mainly by two types …
Reversible CD8 T cell–neuron cross-talk causes aging-dependent neuronal regenerative decline
Aging is associated with increased prevalence of axonal injuries characterized by poor
regeneration and disability. However, the underlying mechanisms remain unclear. In our …
regeneration and disability. However, the underlying mechanisms remain unclear. In our …
Safety, tolerability, and activity of mesenchymal stem cells versus placebo in multiple sclerosis (MESEMS): a phase 2, randomised, double-blind crossover trial
…, L Castellan, M Cellerino, MT Cencioni… - The Lancet …, 2021 - thelancet.com
Background Mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells,
have been proposed as a promising therapeutic option for people with multiple sclerosis on …
have been proposed as a promising therapeutic option for people with multiple sclerosis on …
Distinct modulation of human myeloid and plasmacytoid dendritic cells by anandamide in multiple sclerosis
V Chiurchiu, MT Cencioni, E Bisicchia… - Annals of …, 2013 - Wiley Online Library
Objective The immunopathogenesis of multiple sclerosis (MS) has always been thought to
be driven by chronically activated and autoreactive Th‐1 and Th‐17 cells. Recently, dendritic …
be driven by chronically activated and autoreactive Th‐1 and Th‐17 cells. Recently, dendritic …
Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models
Biochemical modifications of tau proteins have been proposed to be among the earliest
neurobiological changes in Alzheimer's disease (AD) and correlate better with cognitive …
neurobiological changes in Alzheimer's disease (AD) and correlate better with cognitive …
[HTML][HTML] BRCA1, PARP1 and γH2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib
…, S Lavorgna, DF Angelini, MT Cencioni… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Olaparib (AZD-2281, Ku-0059436) is an orally bioavailable and well-tolerated poly(ADP-ribose)
polymerase (PARP) inhibitor currently under investigation in patients with solid tumors. …
polymerase (PARP) inhibitor currently under investigation in patients with solid tumors. …
[HTML][HTML] Acute focal brain damage alters mitochondrial dynamics and autophagy in axotomized neurons
V Cavallucci, E Bisicchia, MT Cencioni, A Ferri… - Cell death & …, 2014 - nature.com
Mitochondria are key organelles for the maintenance of life and death of the cell, and their
morphology is controlled by continual and balanced fission and fusion dynamics. A balance …
morphology is controlled by continual and balanced fission and fusion dynamics. A balance …