User profiles for J. C. Motzkin

Julian Motzkin

Assistant Professor of Neurology - UCSF
Verified email at ucsf.edu
Cited by 1969

Ventromedial prefrontal cortex is critical for the regulation of amygdala activity in humans

JC Motzkin, CL Philippi, RC Wolf, MK Baskaya… - Biological …, 2015 - Elsevier
Background Dysfunction in the ventromedial prefrontal cortex (vmPFC) is believed to play a
pivotal role in the pathogenesis of mood and anxiety disorders. Leading neurocircuitry …

Reduced prefrontal connectivity in psychopathy

JC Motzkin, JP Newman, KA Kiehl… - Journal of …, 2011 - Soc Neuroscience
Linking psychopathy to a specific brain abnormality could have significant clinical, legal,
and scientific implications. Theories on the neurobiological basis of the disorder typically …

Cortical thinning in psychopathy

M Ly, JC Motzkin, CL Philippi, GR Kirk… - American Journal of …, 2012 - Am Psychiatric Assoc
Objective: Psychopathy is a personality disorder associated with severely antisocial behavior
and a host of cognitive and affective deficits. The neuropathological basis of the disorder …

Interpersonal traits of psychopathy linked to reduced integrity of the uncinate fasciculus

RC Wolf, MS Pujara, JC Motzkin… - Human brain …, 2015 - Wiley Online Library
Psychopathy is a personality disorder characterized by callous lack of empathy, impulsive
antisocial behavior, and criminal recidivism. Here, we performed the largest diffusion tensor …

Altered resting-state functional connectivity in cortical networks in psychopathy

CL Philippi, MS Pujara, JC Motzkin… - Journal of …, 2015 - Soc Neuroscience
Psychopathy is a personality disorder characterized by callous antisocial behavior and
criminal recidivism. Here we examine whether psychopathy is associated with alterations in …

Neural correlates of substance abuse: reduced functional connectivity between areas underlying reward and cognitive control

JC Motzkin, A Baskin‐Sommers… - Human brain …, 2014 - Wiley Online Library
Substance use disorders (SUD) have been associated with dysfunction in reward processing,
habit formation, and cognitive‐behavioral control. Accordingly, neurocircuitry models of …

Neural correlates of reward and loss sensitivity in psychopathy

M Pujara, JC Motzkin, JP Newman… - Social Cognitive and …, 2014 - academic.oup.com
Psychopathy is a personality disorder associated with callous and impulsive behavior and
criminal recidivism. It has long been theorized that psychopaths have deficits in processing …

Ventromedial prefrontal cortex mediates visual attention during facial emotion recognition

RC Wolf, CL Philippi, JC Motzkin, MK Baskaya… - Brain, 2014 - academic.oup.com
The ventromedial prefrontal cortex is known to play a crucial role in regulating human social
and emotional behaviour, yet the precise mechanisms by which it subserves this broad …

Subclinical depression severity is associated with distinct patterns of functional connectivity for subregions of anterior cingulate cortex

CL Philippi, JC Motzkin, MS Pujara… - Journal of psychiatric …, 2015 - Elsevier
Depression is a prevalent psychiatric condition characterized by sad mood and anhedonia.
Neuroscientific research has consistently identified abnormalities in a network of brain …

Ventromedial prefrontal cortex damage is associated with decreased ventral striatum volume and response to reward

MS Pujara, CL Philippi, JC Motzkin… - Journal of …, 2016 - Soc Neuroscience
The ventral striatum and ventromedial prefrontal cortex (vmPFC) are two central nodes of
the “reward circuit” of the brain. Human neuroimaging studies have demonstrated coincident …