User profiles for J. C. Motzkin
Julian MotzkinAssistant Professor of Neurology - UCSF Verified email at ucsf.edu Cited by 1969 |
Ventromedial prefrontal cortex is critical for the regulation of amygdala activity in humans
Background Dysfunction in the ventromedial prefrontal cortex (vmPFC) is believed to play a
pivotal role in the pathogenesis of mood and anxiety disorders. Leading neurocircuitry …
pivotal role in the pathogenesis of mood and anxiety disorders. Leading neurocircuitry …
Reduced prefrontal connectivity in psychopathy
Linking psychopathy to a specific brain abnormality could have significant clinical, legal,
and scientific implications. Theories on the neurobiological basis of the disorder typically …
and scientific implications. Theories on the neurobiological basis of the disorder typically …
Cortical thinning in psychopathy
M Ly, JC Motzkin, CL Philippi, GR Kirk… - American Journal of …, 2012 - Am Psychiatric Assoc
Objective: Psychopathy is a personality disorder associated with severely antisocial behavior
and a host of cognitive and affective deficits. The neuropathological basis of the disorder …
and a host of cognitive and affective deficits. The neuropathological basis of the disorder …
Interpersonal traits of psychopathy linked to reduced integrity of the uncinate fasciculus
RC Wolf, MS Pujara, JC Motzkin… - Human brain …, 2015 - Wiley Online Library
Psychopathy is a personality disorder characterized by callous lack of empathy, impulsive
antisocial behavior, and criminal recidivism. Here, we performed the largest diffusion tensor …
antisocial behavior, and criminal recidivism. Here, we performed the largest diffusion tensor …
Altered resting-state functional connectivity in cortical networks in psychopathy
Psychopathy is a personality disorder characterized by callous antisocial behavior and
criminal recidivism. Here we examine whether psychopathy is associated with alterations in …
criminal recidivism. Here we examine whether psychopathy is associated with alterations in …
Neural correlates of substance abuse: reduced functional connectivity between areas underlying reward and cognitive control
JC Motzkin, A Baskin‐Sommers… - Human brain …, 2014 - Wiley Online Library
Substance use disorders (SUD) have been associated with dysfunction in reward processing,
habit formation, and cognitive‐behavioral control. Accordingly, neurocircuitry models of …
habit formation, and cognitive‐behavioral control. Accordingly, neurocircuitry models of …
Neural correlates of reward and loss sensitivity in psychopathy
Psychopathy is a personality disorder associated with callous and impulsive behavior and
criminal recidivism. It has long been theorized that psychopaths have deficits in processing …
criminal recidivism. It has long been theorized that psychopaths have deficits in processing …
Ventromedial prefrontal cortex mediates visual attention during facial emotion recognition
The ventromedial prefrontal cortex is known to play a crucial role in regulating human social
and emotional behaviour, yet the precise mechanisms by which it subserves this broad …
and emotional behaviour, yet the precise mechanisms by which it subserves this broad …
Subclinical depression severity is associated with distinct patterns of functional connectivity for subregions of anterior cingulate cortex
Depression is a prevalent psychiatric condition characterized by sad mood and anhedonia.
Neuroscientific research has consistently identified abnormalities in a network of brain …
Neuroscientific research has consistently identified abnormalities in a network of brain …
Ventromedial prefrontal cortex damage is associated with decreased ventral striatum volume and response to reward
The ventral striatum and ventromedial prefrontal cortex (vmPFC) are two central nodes of
the “reward circuit” of the brain. Human neuroimaging studies have demonstrated coincident …
the “reward circuit” of the brain. Human neuroimaging studies have demonstrated coincident …