… and three SH3 domains in their C-terminal region. While the … -ligase and adaptor protein
c-Cbl, the tyrosine kinase c-Abl and … Reggiedependent recruitment of a CAP/c-Cbl complex was …

… c ) resides in lipid rafts, yet the type of raft and the physiological function of PrP c are unclear…
c with specific antibodies leads to 1) PrP c capping in Jurkat and human peripheral blood T …

The proteins reggie-1 and reggie-2 were originally discovered in neurons during axon
regeneration. Subsequently, they were independently identified as markers of lipid rafts in …

… C. Holt for her advice on the HRP staining of axons in the … retinotectal projection in goldfish
(Stuermer, 1988a, b). It … retinal axons (Stuermer and Vielmetter, 1987a; Stuermer, 1988c), sug…

… with PBS (150 mM NaCl/20 mM sodium phosphate, pH 7.4), scraped into a lysis buffer (25
mM Mes/ 150 mM NaCl/60 mM N-octylglucoside, pH 6.5) and incubated for 30 min at 4 ◦C. …

Prion proteins (PrPs) are key players in fatal neurodegenerative disorders, yet their physiological
functions remain unclear, as PrP knockout mice develop rather normally. We report a …

… Antibodies against the GPI-anchored CAMs (F3 and Thy-1) and L1 were applied to live cells
at either 4C for 1 h or 37C for 45 min. Alternatively, cells were fixed in 4% PFA (5 min at RT) …

… We also show that oligomerization requires the C-terminal but not the N-terminal halves of
reggie-1 and -2. Using deletion constructs, we analysed the functional relevance of the three …

… (−20C) and rinsed at room temperature in PBS (3× 5 minutes). Sections were incubated
with mAb M802 overnight at 4C, washed in PBS for 5 minutes, incubated (1 hour at 37C) with …

… , samples were impregnated overnight at −20C with equal parts of ethanol + LR Gold, … C,
and final embedding and UV-polymerization for 72 h at a temperature set at −35C (rising to −4C …