The mammalian suprachiasmatic nucleus (SCN) is a master circadian pacemaker. It is not
known which SCN neurons are autonomous pacemakers or how they synchronize their daily …

Neurons in the suprachiasmatic nucleus (SCN) function as part of a central timing circuit
that drives daily changes in our behaviour and underlying physiology. A hallmark feature of …

… Michel, and CS Colwell were responsible for the behavioral and electrophysiological
analysis. Finally, we acknowledge J. Asai for expert assistance with the immunocytochemical …

Disruptions in sleep/wake cycles, including decreased amplitude of rhythmic behaviors and
fragmentation of the sleep episodes, are commonly associated with aging in humans and …

Endogenous processes referred to as circadian oscillators generate many of the daily rhythms
in physiology and behavior of a variety of animals including humans. We investigated the …

Type 2 diabetes mellitus (T2DM) is complex metabolic disease that arises as a consequence
of interactions between genetic predisposition and environmental triggers. One recently …

… K + currents were blocked with a combination of Cs + in the pipette and tetraethylammonium
(TEA, 10–20 mM) in the bath and selected Ca 2+ currents were blocked with …

The goal of this study is to investigate the possible circadian regulation of hippocampal
excitability and long-term potentiation (LTP) measured by stimulating the Schaffer collaterals (SC…

… CS–US pairings were comprised of 30 s of white noise (CS), … CS–US pairings were
comprised of 30 s of white noise (CS) … the first CS–US pairing and the 2 min after the last CS–US …

… We have found that VIP regulates a fast delayed rectifier K + current (Itri and Colwell,
unpublished). This current is important for the expression of daily rhythms in the frequency of action …