User profiles for C. A. Hutton

Craig A Hutton

School of Chemistry, University of Melbourne
Verified email at unimelb.edu.au
Cited by 4063

Inhibition of lysine biosynthesis: an evolving antibiotic strategy

CA Hutton, MA Perugini, JA Gerrard - Molecular BioSystems, 2007 - pubs.rsc.org
… Craig Hutton Craig Hutton obtained his undergraduate and PhD degrees from the University
of Adelaide before completing postdoctoral studies at the University of California, Berkeley …

Progress and perspectives on directing group-assisted palladium-catalysed C–H functionalisation of amino acids and peptides

S Shabani, Y Wu, HG Ryan, CA Hutton - Chemical Society Reviews, 2021 - pubs.rsc.org
Hutton Craig Hutton undertook his undergraduate and PhD degrees at the University of
Adelaide before completing postdoctoral studies at the University of California, Berkeley and the …

Inhibitors of lysine biosynthesis as antibacterial agents.

CA Hutton, TJ Southwood, JJ Turner - Mini reviews in medicinal …, 2003 - europepmc.org
Bacterial biosynthesis of lysine has come under increased scrutiny as a target for novel
antibacterial agents as it provides both lysine for protein synthesis and meso-diaminopimelate …

Deprotection of pinacolyl boronate esters via hydrolysis of intermediate potassium trifluoroborates

AKL Yuen, CA Hutton - Tetrahedron letters, 2005 - Elsevier
… of lithium hydroxide at hydrolysing the trifluoroborate may be in part due to the large lattice
enthalpy of the lithium fluoride formed (1047 kJ mol −1 ) 18 and its low solubility in water (ca. …

Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis

…, K Uchida, DA Spiegel, JR Cochrane, CA Hutton… - elife, 2016 - elifesciences.org
10.7554/eLife.19375.001 Metabolic reprogramming toward aerobic glycolysis unavoidably
induces methylglyoxal (MG) formation in cancer cells. MG mediates the glycation of proteins …

Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples

…, T Johanssen, CA McLean, WM Kok, CA Hutton… - Acta …, 2013 - Springer
The formation of low-order oligomers of β-amyloid (Aβ) within the brain is widely believed to
be a central component of Alzheimer’s disease (AD) pathogenesis. However, despite …

Synthesis of the side chain cross-linked tyrosine oligomers dityrosine, trityrosine, and pulcherosine

O Skaff, KA Jolliffe, CA Hutton - The Journal of organic chemistry, 2005 - ACS Publications
An efficient synthesis of dityrosine and the first syntheses of the tyrosine trimers trityrosine
and pulcherosine have been achieved. Protected 3-iodotyrosine underwent tandem Miyaura …

Characterization and identification of dityrosine cross-linked peptides using tandem mass spectrometry

…, KJ Barnham, WM Kok, CA Hutton… - Analytical …, 2017 - ACS Publications
The use of mass spectrometry coupled with chemical cross-linking of proteins has become
a powerful tool for proteins structure and interactions studies. Unlike structural analysis of …

[HTML][HTML] Hormetic potential of methylglyoxal, a side-product of glycolysis, in switching tumours from growth to death

…, K Uchida, DA Spiegel, JR Cochrane, CA Hutton… - Scientific Reports, 2017 - nature.com
… Protein concentration is determined using bicinchoninic acid assay (Pierce, Carlsbad, CA).
Twenty µg of protein were separated on 10 or 12.5% SDS-PAGE and transferred to PVDF …

[HTML][HTML] Effects of PPARγ ligands on TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells

X Tan, H Dagher, CA Hutton, JE Bourke - Respiratory research, 2010 - Springer
… Total protein concentration was measured via a spectrophotometer (Thermoplus, Finland)
using the bicinchoninic acid (BCA) protein assay kit (Bio-Rad, Hercules, CA) with BSA utilised …