Type 2 diabetes mellitus is a progressive and complex disorder that is difficult to treat effectively
in the long term. The majority of patients are overweight or obese at diagnosis and will …

Diabetes mellitus is 1one of the most common chronic diseases in the world, with an estimated
worldwide prevalence of over 176 million in 2000. Furthermore, the prevalence of the …

Dyslipidaemia is common in patients with Type 2 diabetes and is held to be responsible for
considerable CVD-related morbidity and mortality. Patients with Type 2 diabetes are at high …

The blood–brain barrier (BBB) is comprised of specialized endothelial cells that form the
capillary microvasculature of the CNS and is essential for brain function. It also poses the …

Taken orally, the drug dimethyl fumarate (DMF) has been shown to improve functional outcomes
for patients with MS; however, it is unclear how DMF mediates a protective effect. DMF …

Pannexin 1 (Px1, Panx1) and pannexin 2 (Px2, Panx2) form large-pore nonselective
channels in the plasma membrane of cells and were suggested to play a role in the …

Background Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease afflicting
about one third of the world’s population and 30 % of the US population. It is induced by …

Background and Purpose— Stroke is triggered by several risk factors, including influenza
and other respiratory tract infections. However, it is unknown how and in which way influenza …

Mouse embryonic stem (ES) cells grown in serum exhibit greater heterogeneity in morphology
and expression of pluripotency factors than ES cells cultured in defined medium with …

We propose a theoretical framework to analyze the offshoring and reshoring decisions of
firms in the age of automation. Our theory suggests that increasing productivity in automation …