Abstract
Neuronal ion channels are directly associated in vivo with a wide variety of proteins. New classes of channel-associated proteins have been identified recently, including the PSD-95/SAP90 family of channel-clustering molecules and components of the synaptic vesicle release machinery. Recent findings suggest that non-pore-forming subunits of ion channels may also have cell biological functions independent of their effects on channel electrophysiological properties.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Calcium Channels / physiology
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Disks Large Homolog 4 Protein
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Humans
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Intracellular Signaling Peptides and Proteins
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Ion Channel Gating
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Ion Channels / pharmacology*
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Mammals
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Membrane Proteins / physiology
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Models, Neurological
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Nerve Tissue Proteins / physiology*
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Neurons / physiology*
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Neurotransmitter Agents / physiology
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Qa-SNARE Proteins
Substances
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Calcium Channels
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DLG4 protein, human
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Disks Large Homolog 4 Protein
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Intracellular Signaling Peptides and Proteins
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Ion Channels
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Membrane Proteins
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Nerve Tissue Proteins
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Neurotransmitter Agents
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Qa-SNARE Proteins
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postsynaptic density proteins