Polyethyleneimine functionalized single-walled carbon nanotubes as a substrate for neuronal growth

J Phys Chem B. 2005 Mar 17;109(10):4285-9. doi: 10.1021/jp0441137.

Abstract

We report the synthesis of a single-walled carbon nanotube (SWNT) graft copolymer. This polymer was prepared by the functionalization of SWNTs with polyethyleneimine (PEI). We used this graft copolymer, SWNT-PEI, as a substrate for cultured neurons and found that it promotes neurite outgrowth and branching.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Cell Culture Techniques*
  • Cells, Cultured
  • Culture Media
  • Fluoresceins / metabolism
  • Hippocampus / cytology
  • Microscopy, Fluorescence
  • Nanotubes / chemistry*
  • Neurites / physiology
  • Neurons / physiology*
  • Polyethyleneimine / chemistry*
  • Rats
  • Rats, Sprague-Dawley
  • Spectrophotometry, Infrared

Substances

  • Culture Media
  • Fluoresceins
  • Polyethyleneimine
  • fluorexon