Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity

J Clin Invest. 2001 Jan;107(1):13-9. doi: 10.1172/JCI11837.

Authors

G Zhang¹, S Ghosh

Affiliation

¹ Section of Immunobiology and Department of Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, USA.

PMID: 11134172
PMCID: PMC198554
DOI: 10.1172/JCI11837

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Amino Acid Sequence
Animals
Conserved Sequence
Humans
Immunity, Innate
Lipopolysaccharide Receptors / metabolism
Molecular Sequence Data
NF-kappa B / metabolism*
Phylogeny
Proto-Oncogene Proteins c-rel / metabolism
Receptors, Cell Surface / genetics*
Receptors, Cell Surface / metabolism*
Signal Transduction

Substances

Lipopolysaccharide Receptors
NF-kappa B
Proto-Oncogene Proteins c-rel
Receptors, Cell Surface