Abstract
In dendritic cells, macropinocytosis is downregulated during maturation and antigen presentation. New studies indicate a key role for Rho-family GTPases in this regulation, but what these proteins are actually doing remains a mystery.
MeSH terms
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Animals
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Antigens / metabolism
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Dendritic Cells / cytology
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Dendritic Cells / physiology*
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Humans
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Macrophages / physiology
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Pinocytosis
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cdc42 GTP-Binding Protein / metabolism*
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rac GTP-Binding Proteins / metabolism*
Substances
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Antigens
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cdc42 GTP-Binding Protein
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rac GTP-Binding Proteins