Dream phenomena induced by chronic levodopa therapy

J Neural Transm. 1978;43(2):143-51. doi: 10.1007/BF01579073.

Abstract

Twenty-seven of eighty-eight (30.7%) Parkinsonian patients on chronic levodopa or levodopa/carbidopa therapy developed drug related dream phenomena. The patients reported three separate types of new dreams which we have classified as vivid dreams, night terrors and nightmares. These dreams are correlated to the duration of levodopa therapy although the mechanism of their production is unclear.

MeSH terms

  • Adult
  • Aged
  • Carbidopa / adverse effects
  • Carbidopa / therapeutic use
  • Delusions / chemically induced
  • Dreams / drug effects*
  • Female
  • Hallucinations / chemically induced
  • Humans
  • Illusions / drug effects
  • Levodopa / adverse effects*
  • Levodopa / therapeutic use
  • Long-Term Care
  • Male
  • Middle Aged
  • Parkinson Disease / drug therapy
  • Psychoses, Substance-Induced / etiology

Substances

  • Levodopa
  • Carbidopa