Genetic Mouse Models of Alzheimer's Disease

Mineur, Yann S.; McLoughlin, Declan; Crusio, Wim E.; Sluyter, Frans

doi:https://doi.org/10.1155/NP.2005.299

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Pathological Changes in Memory Processing

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Volume 12 | Article ID 981585 | https://doi.org/10.1155/NP.2005.299

Genetic Mouse Models of Alzheimer's Disease

Yann S. Mineur,¹Declan McLoughlin,²Wim E. Crusio,³and Frans Sluyter⁴

Abstract

In the current minireview, we focus on genetic mouse models of Alzheimer's disease (AD). Because various excellent, up-to-date reviews, special issues, and reliable websites are already dedicated to the genetics of Alzheimer's disease in general and of animal models in particular, this review is not meant to be comprehensive. Rather, we aim to steer the Alzheimer's novice through the recent mouse literature on AD. Special attention will be paid to genetic models that have been tested behaviorally.

Copyright

Copyright © 2005 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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