Elsevier

Developmental Brain Research

Volume 98, Issue 2, 20 February 1997, Pages 287-290
Developmental Brain Research

Short communication
Blockade of afferent impulse activity disrupts on/off sublamination in the ferret lateral geniculate nucleus

https://doi.org/10.1016/S0165-3806(96)00188-5Get rights and content

Abstract

The ferret retinogeniculate projection is organized into on/off sublaminae within each eye-specific layer. The role of afferent activity in the formation of these sublaminae was examined. We report that when the activity of retinal ganglion cells is blocked with tetrodotoxin during postnatal weeks three and four, on/off sublamination is disrupted, supporting a role for afferent activity in the formation of this pattern.

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