Elsevier

Vision Research

Volume 39, Issue 15, July 1999, Pages 2469-2476
Vision Research

Synaptic mechanisms of bipolar cell terminals

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Abstract

Giant synaptic terminals of goldfish bipolar neurons allow direct studies of presynaptic mechanisms underlying neurotransmitter release and its modulation. Calcium influx via L-type calcium channels of the terminal triggers synaptic vesicle exocytosis, which can be monitored in isolated terminals by means of the associated changes in membrane capacitance. Information about the kinetics and calcium dependence of synaptic exocytosis has been obtained from capacitance measurements in these ribbon-type synaptic terminals.

Keywords

Synaptic mechanisms
Terminals
Bipolar neurons

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