Impact of reoxygenation on the glutathione to glutathione disulfide ratio in the brain
| Treatment | Normoxic | Reoxygenation (1 h) |
|---|---|---|
| Saline | 1.00 ± 0.21a | 0.49 ± 0.12b |
| Caffeine | 0.88 ± 0.15a | 0.87 ± 0.10a |
| NAC | 0.82 ± 0.02a | 1.03 ± 0.03a |
Wild type mice were exposed to normoxia or hypoxia for 2 h. Whole brains were harvested and analyzed for GSH and GSSG concentrations. Results are expressed as relative change in GSH/GSSG ratio, means ± SEM; n = 4. Results within individual rows without a common superscript are different (p < 0.05).