Electrophysiological properties of CRH-GFP neurons in wild-type and Gabrd−/− mice under stress and THDOC conditions
| sIPSC frequency(Hz) | sIPSC PeakAmplitude(pA) | sIPSC tw (ms) | Tonic current(pA) | Firing Rate(Hz) | |
|---|---|---|---|---|---|
| Wild-type nACSF | 11.4 ± 2.4 | 56.9 ± 6.8 | 12.8 ± 1.2 | 11.2 ± 2.5 | 5.5 ± 1.0 |
| Wild-type THDOC | 11.3 ± 2.3 | 54.0 ± 5.2 | 13.0 ± 1.0 | 20.9 ± 2.5* | 2.8 ± 0.6* |
| Gabrd−/− nACSF | 3.1 ± 1.4 | 8.4 ± 0.8 | |||
| Gabr−/− THDOC | 4.5 ± 1.2 | 9.8 ± 1.4 |
↵* denotes significance compared to wild-type nACSF.