Table 1.

Synaptic protein composition in NL1 KO brain

%SEMp value
β-Catenin106.67547.8636550.5225598
CaMKIIα89.192369.9842380.5153004
Complexin1106.13282366.2097502330.428415248
CSP86.682854.5917860.0326469*
GABAα-Rα96.379078.5325680.7916562
GluR1103.82897038.2882856360.813943664
Liprin88.461952.0253090.02345723*
Munc-1878.836072.232590.003578847**
NL3129.38258826.800798280.02431589*
NL2104.985367.88801850.8019042
NR178.0998230419.446765860.45496166
NR2A89.756558.7600290.388649
NR2B93.488021446.3624188680.509075447
NSF91.735667.7699680.403433
Nrx-α82.3306523.29196120.0354927*
Nrx-β80.4425765.52395260.0325197*
PSD-95114.27358748.5997069970.240376141
Rab3A76.611928.1365210.3786824
Rabphilin94.499665.8167950.5273652
SCAMP106.759612.578340.7664692
SNAP-2598.745842.9422590.7681499
Synaptobrevin-2107.78067.4158250.6034307
Synapsin-1a/b118.60788715.1546509330.038798877*
Synapsin-2b109.41518588.0290060220.440344385
Synaptophysin102.64273.1311890.5091538
Synaptotagmin-199.251041.8459060.794641
VAChT121.02597.8992160.2178337
VGAT102.208116.370490.9298164
VGlut195.7644712.954710.8080348
  • Protein levels (percentage of wild-type) in P40 NL1 KO brain homogenate, SEM, and p value (Student's t test) are listed (wild type, n = 4; KO, n = 4). Nrx, Neurexin.

  • *p < 0.05;

  • **p < 0.01 compared to WT.