IC50 of Tat-NR2B9c for NMDA receptor interactions
| PDZ ligand | PDZ protein | Tat-NR2B9c IC50 |
|---|---|---|
| NMDAR2A | PSD-95d2 | 0.5 μm |
| DLG1d2 | ∼10 μm | |
| NeDLG1,2 | ∼7 μm | |
| KIAA 0973 | ∼9 μm | |
| TIP-1 | ∼7 μm | |
| DLG2d2 | ∼3 μm | |
| NMDAR2B | PSD-95d2 | ∼8 μm |
| DLG1/SAP97d2 | >10 μm | |
| NeDLG/SAP102d1,d2 | ∼7 μm | |
| KIAA 0973 | >10 μm | |
| TIP-1 | ∼10 μm | |
| DLG2/PSD-93d2 | >10 μm | |
| NMDAR2C | PSD-95d2 | 0.75 μm |
| DLG1d2 | 0.5 μm | |
| NeDLG1,2 | ∼1.1 μm | |
| KIAA 0973 | ∼1.5 μm | |
| TIP-1 | 1 μm | |
| DLG2d2 | ∼1.2 μm | |
| nNOS internal | PSD-95d2 | 0.2 μm |