Cortex | Cerebellum | Olfactory bulb | Remaining areas | Total | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Estimates | CV | Estimates | CV | Estimates | CV | Estimates | CV | Estimates | CV | |
Weight (mg) | 770 ± 113 | 0.15 | 272 ± 38 | 0.14 | 77 ± 23 | 0.30 | 683 ± 153 | 0.22 | 1802 ± 313 | 0.17 |
n cells (×106) | 76.71 ± 3.02 | 0.04 | 168.18 ± 12.57 | 0.07 | 20.87 ± 5.80 | 0.28 | 65.90 ± 9.64 | 0.15 | 331.65 ± 8.84 | 0.03 |
Cells (×103)/mg | 101.52 ± 17.40 | 0.17 | 631.24 ± 128.58 | 0.20 | 272.43 ± 33.89 | 0.12 | 99.57 ± 23.97 | 0.24 | 188.79 ± 36.65 | 0.19 |
Percentage of NeuN+ nuclei | 40.58 ± 5.34 | 0.13 | 82.78 ± 3.24 | 0.04 | 53.60 ± 4.28 | 0.08 | 28.12 ± 3.14 | 0.11 | 60.31 ± 2.35 | 0.04 |
n neurons (×106) | 31.02 ± 3.03 | 0.10 | 139.17 ± 11.19 | 0.10 | 11.26 ± 3.68 | 0.10 | 18.68 ± 4.24 | 0.10 | 200.13 ± 12.17 | 0.06 |
Neurons (×103)/mg | 41.09 ± 8.00 | 0.19 | 522.69 ± 108.85 | 0.21 | 146.92 ± 27.50 | 0.19 | 27.81 ± 6.17 | 0.22 | 113.98 ± 23.16 | 0.20 |
n non-neuronal cells (×106) | 45.69 ± 5.68 | 0.12 | 29.01 ± 6.28 | 0.08 | 9.61 ± 2.42 | 0.33 | 47.22 ± 5.98 | 0.23 | 131.52 ± 6.11 | 0.05 |
Percentage of brain weight | 42.86 ± 1.74 | 0.04 | 15.17 ± 1.00 | 0.06 | 4.24 ± 0.77 | 0.18 | 37.72 ± 2.55 | 0.07 | ||
Percentage of all cells | 23.15 ± 1.23 | 0.05 | 50.69 ± 3.16 | 0.06 | 6.31 ± 1.83 | 0.29 | 19.86 ± 2.74 | 0.14 | ||
Percentage of all neurons | 15.48 ± 0.94 | 0.06 | 69.57 ± 4.37 | 0.06 | 5.64 ± 1.90 | 0.34 | 9.31 ± 1.96 | 0.21 |
Values are mean ± SD. CV = SD/mean. n cells, total number of cells (in millions); Cells (×103)/mg, cell density per milligram of tissue (in thousands); n neurons, total number of neurons (in millions); Neurons (×103)/mg, neuronal density per milligram of tissue (in thousands); n non-neuronal cells, total number of non-neuronal cells (in millions, defined as n cells - n neurons). Large SD and CV values for olfactory bulb weight can be partly explained by the difficulty of dissecting this structure undamaged.