Table 1.

Individual delayed-response performance across testing conditions

Monkey Baseline D1 agonist Post-D1 agonist
Aged
TYR 66.60 ± 1.84 82.41 ± 1.52¥
RAM 70.48 ± 1.58 80.00 ± 1.89¥ 77.33 ± 1.57¥
SYB 69.32 ± 1.84 90.58 ± 1.74¥ 93.82 ± 0.95¥
AGA 65.00 ± 1.71 75.71 ± 2.22¥ 80.86 ± 1.27¥*
Young
JOA 69.60 ± 2.62 70.39 ± 1.64 68.90 ± 2.90
MAR 76.00 ± 2.00 69.00 ± 2.00¥ 71.00 ± 1.99
ISL 72.35 ± 2.50 63.43 ± 3.31¥ 74.50 ± 3.14*
  • Shown are the mean ± SEM percentage correct for four aged and three young monkeys across baseline, the last two blocks of D1 agonist treatment, and the post-D1 period. Symbols indicate that performance under a particular condition differs significantly from another condition at an α-level of 0.05 as indicated by factorial ANOVA with Scheffe post hoc comparisons (¥significant versus baseline; *significant versus D1 agonist). Note: The blank space for monkey TYR under the D1 agonist column reflects the fact that this monkey did not receive the final two blocks of treatment during the D1 agonist testing period because of temporary illness. It is of note, however, that despite the abbreviated D1 regimen in this ≥30-year-old monkey, significant improvement in spatial working memory was observed during the post-D1 agonist testing period.