Control | Dark-reared | |||||||
---|---|---|---|---|---|---|---|---|
P9 | P11–13 | P15 | P21 | 6 weeks | P15 | P21 | 6 weeks | |
Number of cells (retinas) | 57 (3) | 166 (8) | 158 (4) | 132 (4) | 89 (4) | 140 (5) | 95 (4) | 165 (6) |
Firing rate (Hz) | ||||||||
Mean | 0.30 | 0.45 | 0.96 | 0.70 | 2.40 | 0.95 | 1.29 | 2.49 |
25% | 0.16 | 0.18 | 0.32 | 0.09 | 0.13 | 0.37 | 0.32 | 0.46 |
50% | 0.26 | 0.33 | 0.68 | 0.38 | 0.60 | 0.77 | 0.89 | 1.42 |
75% | 0.36 | 0.57 | 1.34 | 0.92 | 4.09 | 1.17 | 1.97 | 3.68 |
Burst duration (sec) | ||||||||
Mean | 0.87 | 0.45 | 0.29 | 0.25 | 0.19 | 0.33 | 0.15 | 0.27 |
25% | 0.56 | 0.29 | 0.17 | 0.08 | 0.11 | 0.11 | 0.08 | 0.08 |
50% | 0.86 | 0.38 | 0.23 | 0.17 | 0.17 | 0.14 | 0.08 | 0.14 |
75% | 1.24 | 0.59 | 0.32 | 0.32 | 0.29 | 0.20 | 0.14 | 0.23 |
Fano factor | ||||||||
Mean | 18.10 | 9.04 | 7.74 | 4.48 | 6.00 | 7.37 | 2.63 | 6.93 |
25% | 11.30 | 5.93 | 4.80 | 2.31 | 3.13 | 4.18 | 1.53 | 4.15 |
50% | 15.10 | 8.49 | 6.69 | 4.27 | 5.09 | 6.50 | 2.38 | 5.72 |
75% | 21.70 | 11.10 | 10.40 | 6.10 | 7.53 | 9.36 | 3.38 | 7.65 |
Interwave interval (sec) | ||||||||
Mean | 72.23 | 58.56 | 109.83 | 141.03 | ||||
25% | 47.50 | 36.00 | 72.25 | 56.00 | ||||
50% | 64.00 | 47.00 | 91.50 | 92.00 | ||||
75% | 87.00 | 70.00 | 139.75 | 194.00 | ||||
Wave speed (μm/sec) | ||||||||
Mean | 199.80 | 273.90 | NA | NA | ||||
SD | 19.89 | 33.23 | NA | NA | ||||
Correlation index intercept | 69.04 | 10.12a | 6.92 | 5.65 | 3.16 | 5.43 | 1.84 | 2.46 |
22.18a | ||||||||
Half-maximum (μm) | 151.67 | 275.06a | 246.67 | 276.15 | 387.23 | 301.50 | 570.96 | 465.51 |
173.72a |
Non-normality of the firing rate, burst duration, and Fano factor distributions necessitated presentation of the quartiles [(1st-25%, 2nd-50% (median), 3rd-75%] of these distributions to more accurately represent the data. Wave speed was not calculated at P15 because no wavefront was easily discriminated. Interwave interval was not calculated at P21 or 6 weeks because waves were not present at these ages. The correlation index intercept is the value of the fitted exponential curve at the intercept with the y-axis; the half maximum is the distance over which the curve falls to half its initial value.
aFor the correlation index parameters, the values for P11 (top) and P13 (bottom) are given separately.