Table 1.

Properties of spontaneously generated spike trains during development

ControlDark-reared
P9P11–13P15P216 weeksP15P216 weeks
Number of cells (retinas)57 (3)166 (8)158 (4)132 (4)89 (4)140 (5)95 (4)165 (6)
Firing rate (Hz)
 Mean0.300.450.960.702.400.951.292.49
 25%0.160.180.320.090.130.370.320.46
 50%0.260.330.680.380.600.770.891.42
 75%0.360.571.340.924.091.171.973.68
Burst duration (sec)
 Mean0.870.450.290.250.190.330.150.27
 25%0.560.290.170.080.110.110.080.08
 50%0.860.380.230.170.170.140.080.14
 75%1.240.590.320.320.290.200.140.23
Fano factor
 Mean18.109.047.744.486.007.372.636.93
 25%11.305.934.802.313.134.181.534.15
 50%15.108.496.694.275.096.502.385.72
 75%21.7011.1010.406.107.539.363.387.65
Interwave interval (sec)
 Mean72.2358.56109.83141.03
 25%47.5036.0072.2556.00
 50%64.0047.0091.5092.00
 75%87.0070.00139.75194.00
Wave speed (μm/sec)
 Mean199.80273.90NANA
 SD19.8933.23NANA
Correlation index intercept69.0410.12a6.925.653.165.431.842.46
22.18a
Half-maximum (μm)151.67275.06a246.67276.15387.23301.50570.96465.51
173.72a
  • Non-normality of the firing rate, burst duration, and Fano factor distributions necessitated presentation of the quartiles [(1st-25%, 2nd-50% (median), 3rd-75%] of these distributions to more accurately represent the data. Wave speed was not calculated at P15 because no wavefront was easily discriminated. Interwave interval was not calculated at P21 or 6 weeks because waves were not present at these ages. The correlation index intercept is the value of the fitted exponential curve at the intercept with the y-axis; the half maximum is the distance over which the curve falls to half its initial value.

  • aFor the correlation index parameters, the values for P11 (top) and P13 (bottom) are given separately.