Genotype | Neurological deficit scores4-a | |||||
---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | 4 | Mean ± SEM4-b | |
Wt | 3 | 7 | 5 | 0 | 1 | 1.31 ± 0.25 |
Sod1+/−uc | 0 | 1 | 2 | 3 | 3 | 2.89 ± 0.354-160 |
Sod1+/−cep | 0 | 4 | 9 | 2 | 1 | 2.00 ± 0.204-150 |
↵F4-a Neurological deficit scores of 0–4: 0, no neurological deficit; 1, failed to extend right forepaw; 2, circled to the right; 3, fell to the right; 4, unable to walk spontaneously. Each value represents the number of animals in the respective scores.
↵F4-b Each value represents mean ± SEM of neurological deficit scores;
↵F4-150 P < 0.05,
↵F4-160 P < 0.01, significantly different from Wt mice (Mann–Whitney Utest).