Figure 1.
Interregional correlations in fMRI signal during the observation of angry hand movements. a, LV1 identified a combination of brain regions that, as a whole, correlated with the RPI scores. Note that high correlations are observed only for fMRI signal measured during the observation of angry hand movements. b, Brain scores (weighted sum of all voxels in an image for each subject, using the weights derived from the brain LV1) derived from the fMRI signal measured during angry hand movements plotted as a function of RPI. c, Locations of brain regions identified by LV1; only regions visible on the lateral surface of the left and right hemispheres are shown. d, Correlation matrices depicting interregional correlations of fMRI signal measured during the observation of angry hand movements, as revealed by LV1, in subjects with high (left) and low (right) RPI. The high- and low-RPI subgroups correspond to the subjects with RPI scores above and below the group median, respectively. The region labels match those included in Table 1. e, Multidimensional scaling (MDS) representations of the interregional correlations of the 26-deletions matrix depicted above; in the MDS 2-deletions plots, strongly correlated regions are placed close together. Note, for example, the close grouping of premotor (F03 and F04) and prefrontal (F08 and F09) frontocortical regions. The region labels match those included in Table 1. F01, Premotor cortex, dorsal, left; F02, premotor cortex, dorsal, right; F03, premotor cortex, ventral, left; F04, premotor cortex, ventral, right; F05, frontal operculum, right; F06, cingulate motor area, left; F07, insula, anterior, left; F08, prefrontal cortex, ventrolateral, right; F09, prefrontal cortex, dorsolateral, left; F10, prefrontal cortex, dorsolateral, right; F11, prefrontal cortex, ventrolateral, left; F12, anterior cingulate cortex, right; F13, orbito-frontal cortex, lateral, left; F14, prefrontal cortex, medial; P01, posterior cingulate cortex; P02, precuneus, left; P03, parietal cortex, dorsolateral, right; P04, parietal cortex, dorsomedial, right; T01, superior temporal sulcus, middle, right; T02, superior temporal sulcus, posterior, right; T03, hippocampus, right; O01, fusiform gyrus, left; CN, caudate nucleus, right; CB1, cerebellum, right; CB2, cerebellum, right; SC, superior colliculus, right.